Medicine

A 31-year-old woman is evaluated because of daily wheezing and breathlessness that limit her activities…

A 31-year-old woman is evaluated because of daily wheezing and breathlessness that limit her activities several times a week. Medical history is otherwise unremarkable. She has never smoked. She is diagnosed with moderate persistent asthma. In addition to a short-acting 32-agonist, which of the following is the most appropriate treatment?

  1. A Add a low-dose inhaled corticosteroid and long-acting B2-agonist الإجابة الصحيحة
  2. B Add a low-dose inhaled corticosteroid
  3. C Add a leukotriene antagonist
  4. D Add thiophylline

الشرح

Core Concept: Moderate persistent asthma requires combination controller therapy to reduce underlying airway inflammation and provide long-lasting bronchodilation, preventing exacerbations and daily symptoms.

Clinical Presentation:

  • Daily symptoms, nighttime awakenings >1x/week, and limitation of normal activities.

Diagnosis:

  • First-line tool: Spirometry showing reversible airflow obstruction.
  • Gold standard: Clinical classification based on symptom frequency and lung function impairment.

Management:

  • Acute: SABA for quick relief of bronchospasm.
  • Long-term/Definitive: The combination of an inhaled corticosteroid (ICS) and a long-acting beta-2 agonist (LABA) is the gold standard step-up therapy for moderate persistent asthma to achieve optimal symptom control.

40 سؤالاً مجاناً مع حساب

الأسئلة المنشورة هنا عيّنة ثابتة. أنشئ حساباً مجانياً لتتدرب على بنك الأسئلة الكامل، مع تحليل أدائك حسب التخصص وصفحة لمراجعة أخطائك.

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